Objective: To study the protective effect of ligustrazine on vascular endothelial cells (VEC) in the early stage of burn. Method: Guinea pigs were scalded to 30%TBSA full-thickness and were divided into treatment group (n=48) and resuscitation group (n=48). And in control group (n=8), the animals were not scalded. In resuscitation group, animals were given balanced fluid for resuscitation, while in treatment group, in addition to balanced fluid, ligustrazine was administered. Plasma endothelin and nitric ox...