【摘要】 1目的　探讨糖类抗原 5 0 (CA5 0 )和糖类抗原 19- 9(CA1 9- 9)对良恶性腹水鉴别诊断的价值。 2方法分别测定良性和恶性腹水病人血清和腹水的 CA5 0 ,CA1 9- 9水平 ,用并联法评价多项肿瘤标志物联合应用对良恶性腹水的诊断价值。 3结果　 5 0例恶性腹水病人血清和腹水中 CA5 0 ,CA1 9- 9水平均显著高于良性腹水病人 (t=7.2 1～7.5 2 ,P<0 .0 1)。血清、腹水 CA5 0 和 CA1 9- 9联合检测对恶性腹水诊断的灵敏度达 94%和 92 % .4结论　 CA5 0 ,CA1 9- 9联合检测可使恶性腹水诊断的灵敏度明显增高 ,对鉴别诊断良恶性腹水有一定的价值更多还原

【Abstract】 Objective\ To evaluate CA 50 and CA 19 9 in the differential diagnosis of benign and malignant ascites.\ Methods\ Two tumor markers,CA 50 and CA 19 9 in ascites and serum were measured in 50 patients with malignant ascites and 50 patients with benign ascites.\ Results\ Ascites and serum levels of CA 50 and CA 19 9 in patients with malignant ascities were significantly higher than those in patients with benign ascites ( t=7.21-7.52,P <0.01).\ Conclusion\ Combination of two tumor markers increases sensitivity in diagnosis of benign and malignant ascites. [更多还原