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全天血糖谱的临床应用

Clinical application of blood glucose profile

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【作者】 顾耀李文君王小燕石莹王吉影徐乃馨史京衡沈希康

【Author】 GU Yao, LI Wenjun, WANG Xiaoyan, et al. Department of Endocrinology, Shanghai Railway Central Hospital, Tong Ji University, Shanghai 200072

【机构】 同济大学医学院附属铁路医院

【摘要】 目的 设计检测全天血糖谱以客观反映病人血糖的动态改变。方法  1型、2型及初发病人共386例。新入院病人当天测全天定时血糖谱 ,每隔 4天测 1次 ,据此调整药物。根据血糖谱归类 ,分析。结果 根据全天血糖谱 ,糖尿病病人血糖大致分成“完全未控制型”占 33.6 % ,“餐后高血糖型”占 31.4% ,“黎明高血糖型”占 12 .9% ,“日间高血糖型”占 12 .7% ,“反应性高血糖型”即“Somogyi效应型”占 9.4%。各型都可能与其不同的治疗背景相关。同时 ,全天血糖谱使低血糖发现率增加 ,发现低血糖占 2 0 .7% ,尤以无症状居多 ,占低血糖反应中的 87%。结论 应用全天血糖谱可较准确地估计病人的血糖控制情况 ,也能及早发现无症状性低血糖。

【Abstract】 Objective For evaluating the accuracy of therapy, we designed a 24 hour blood glucose profile as a guide of medication for diabetics. Methods Both type 1 and type 2 inpatients were recruited in our department during April 1996 and March 1998. The 24 hour blood glucose profile included that determined before and 2 hours after the three meals and before sleep which was done after admitted to the hospital and then every 4 days for modification of drug dosages. Results Basing on this, the blood sugar pattern of the diabetic patients could be divided into five types, i.e. totally uncontrolled (33.6%), postprandial hyperglycemia (31.4%), hyperglycemia at dawn (12.9%), daytime hyperglycemia (12.7%), and Somogyi effect (9.4%). Each type could be related to the treatment background. Concomitently, the rate of discovery of hypoglycemia was found to be 20.7%, especially the symptomatic ones which accounted for 87% of the total hypoglycemic cases. Conclusion This profile is good for assessment of blood sugar control and early discovery of asymptomatic hypoglycemia. (Shanghai Med J, 2000,23∶672 674)

  • 【文献出处】 上海医学 ,SHANGHAI MEDICAL JOURNAL , 编辑部邮箱 ,2000年11期
  • 【分类号】R587.1
  • 【被引频次】5
  • 【下载频次】75
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