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Ⅲ型危重型重症肌无力的外科治疗

Surgical treatment of critical type of myasthenia gravis

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【作者】 陈志明姚亚其庞烈文陆轩马勤运毛履琰

【Author】 CHEN Zhiming, YAO Yaqi, PANG Liewen, et al. Department of Cardiothoracic Surgery, Huashan Hospital, Shanghai Medical University, Shanghai 200040

【机构】 上海医科大学华山医院胸外科

【摘要】 目的 总结手术治疗Ⅲ型危重型重症肌无力的经验。方法 分析我院1990 年4 月至1999 年3月38 例Ⅲ型危重型重症肌无力手术治疗的效果。手术均在全麻下进行,切除胸腺及清扫前纵隔脂肪组织。结果 术后因吸呼困难或危象行气管切开19 例20 次。无围手术期死亡,平均住院(48 .6 ±36 .6)d ,所有病人出院或转科前症状均有不同程度的改善。结论 Ⅲ型危重型重症肌无力病人术后极易发生危象,预防性或及时气管切开辅助呼吸是抢救危象病人有效而安全的措施。术前准备不必强调一定模式,伴发其他免疫性疾病( 主要为甲亢) 并非手术禁忌证。

【Abstract】 Objective To summarize the authors’ clinical experience on the surgical treatment of critical type of myasthenia gravis (MG). Method A series of 38 patients with critical type of MG treated by thymectomy between 1990 and 1999 were reviewed. There were 14 males and 24 females with a mean age of (36.10±12.15) years. Fifteen patients developed crisis for twenty times before operation. Results Postoperatively, nineteen patients developed crisis by twenty times, no perioperative death occurred. All patients were discharged with improvement.Conclusion There was a trend toward crisis in the critical type of MG, timely tracheotomy with auxiliary ventilation is an effective and safe measure for the crisis. Unique preoperative preparation should not be overemphasized, and if there is coexiastent autoimmune disease, (mainly hyperthyroidism) operation is not contraindication.(Shanghai Med J, 2000,23∶ 14 15)

【关键词】 重症肌无力外科治疗
【Key words】 Myasthenia gravisSurgical treatment
  • 【文献出处】 上海医学 ,SHANGHAI MEDICAL JOURNAL , 编辑部邮箱 ,2000年01期
  • 【分类号】R746.1
  • 【被引频次】6
  • 【下载频次】52
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