【摘要】 透析器内凝血是维持性血液透析病人常见的问题之一，透析器内凝血后可使透析膜的通 透性下降，可直接影响透析效果。另外多次出现透析器内凝血给透析病人造成血液的大量丢失， 更加重了患者的贫血。凝血后透析器的丢弃也加重了患者的经济负担。目的：本方法探索出一条 简便易行，安全可靠的抗凝方法。方法：３０例透折患者，男１８例，女１２例，透析过程中病人的肝素 量按照常规应用，平时每日口服阿司匹林一次，每次４０ｍｇ。透析前一天睡前服１６０ｍｇ。结果：透析 器内凝血的血透病人经口服阿司匹林后均收到了满意的效果，其中８０％的病人服药后透析器内凝 血现象完全消失，２０％的病人虽然透析器内仍有少量凝血，但其程度较前有明显减轻。结论：对透 析器内发生凝血的血液透析病人用阿司匹林抗凝，既简单方便，又能收到较好的临床效果。本方 法可提高血液透析病人的透析质量，但必须按时按量服药。更多还原

【Abstract】 Background Blood coagulation in dialyser is commonly encountered in patients during performance of hemodialysis, and the permeability of the dialyser would be thus reduced, and blood loss may increase and results in severe anemia. Moreover, the therapeutic cost for a patient may largely be increased. A simple and convenient approach for lessening the blood coagulation in dialyser during hemodialysis was introduced in this paper. Methods: In this study, totally 30 cases (18 males, 12 fermales) were observed. During dialysis, heparin was regularly given, and aspirin orally administered 40mg once daily. Single dose aspirin of 160mg was administered just before sleep, the day prior to the procedure of applying hemodialysis. Results: The patients receiving oral aspirin had shown satisfactory results, 80% patients without the occurrence of blood coagulation in dialyser, and 20% patients showing small amount of blood coagulation, however, all of them got much better in conditions as compared to those without receiving aspirin. Conclusions: Aspirin used for anticoagulation is a simple, convenient, less - costed and effective approach. However, the drug aspirin should be administered regularly in order.更多还原