【摘要】 采用 Dot- ELISA法定量测定了 6 8例不同贫血患者的血清转铁蛋白受体 (s Tf R)水平 ,发现缺铁性贫血、溶血性贫血和急性失血性贫血患者 s Tf R均显著高于正常人 (P<0 .0 0 1) ;而慢性再生障碍性贫血患者 s Tf R显著低于正常人 (P<0 .0 0 1)。缺铁性贫血 s Tf R水平与血清铁蛋白水平呈负相关 (P<0 .0 0 5) ,溶血性贫血 s Tf R与网织红细胞计数呈正相关 (P<0 .0 0 5) ,s Tf R可以反映机体贮存铁和骨髓红细胞系造血活动。认为 s Tf R测定为诊断缺铁性贫血和判断骨髓红细胞生成的一项具有实用价值的新指标。更多还原

【Abstract】 WT5BZ]To study the clinical application of serum transferrin receptor(sTfR),the sTfR levels in 68patients with various of anemia were determined by using of a dot immunoperoxidase assay(DIPA) Compared with the normal values,the levels were significantly higher in iron deficiency anemia(IDA),hemolytic anemia(HA) and acute hemorrhagic anemia(AHA)(P<0 001),but significantly lower in chronic aplastic anemia(CAA)(P<0 001) The level of sTfR in IDA correlated negatively with the level of serum ferritin(P<0 05),the level of sTfR in HA correlated with the count of reticulocytes(P<0 05) The level of sTfR shows the condition of the stored iron and erythropoiesis We Conclude the detection of sTfR is a new target in the diagnosis of IDA and the judge of erythropoiesis [WT5HZ]更多还原