【摘要】 目的 :研究体感诱发电位 (SEP)监测在颈髓手术中的可行性和可靠性。方法 :选择 34例颈髓手术病例 ,对两侧正中神经分别进行刺激 ,记录相应SEP的N2 0 波形。若术中N2 0 发生明显变化 (潜伏期延长超过 1ms或波幅降低超过 5 0 % ) ,即通知术者调整操作。结果 :有 4例因疾病的影响记录不到波形而放弃监测 ;在进行监测的 30例中 ,出现 2例假阴性 ,无假阳性发生 ,术中SEP变化与术后神经功能改变有明显的相关性 (P <0 0 1)。结论 :颈髓手术中 ,尽管可能出现假阴性结果 ,SEP仍是一种比较可靠的特异性很高的神经生理监测方法。更多还原

【Abstract】 Objective:To study the feasibility and reliability of median nerve somatosensory evoked potentials (SEP) monitoring in cervical spinal surgery.Methods: N 20 wave of SEP was recorded by stimulating the bilateral median nerves in 34 patients undergoing cervical spinal procedure by intravenous anesthesia.As soon as N 20 waveform changed significantly(latency increased more than 1 ms or amplitude decreased more than 50% baseline),the surgeon was informed and the operative procedure was modified whenever possible.Results:Monitoring was given up in four patients as the SEP wave form could not be recorded because of the effect of disease.In 30 cases monitored by SEP,there were 2 false-negative results,and no false-positive results occurred.The significant correlation was noted between intraoperative SEP changes and postoperative neurologic alterations( P <0 01).Conclusion:Though false-negative results may occur,SEP recording might be aveliable and highly specific method for intraoperative monitoring.更多还原