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待米酮的硫代磷酸酯类化合物合成及生物活性研究

The Synthesis of Thiophosphate Derivatives of Dimedone and Their Antitumor Activity

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【作者】 徐凤波杨华铮陈彬刘华银

【Author】 Xu Fengbo et al (Institute of Elemento-Organic Chemistry,National key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin 300071)

【机构】 南开大学元素有机化学研究所!国家元素有机化学重点实验室天津300071天津30

【摘要】 报道一系列 12种待米酮硫代磷酸酯的合成和生物活性测定结果 ,并用1 HNMRIR、元素分析对这些新化合物进行了结构表证。讨论了这类化合物的波谱性质和生物活性及其随取代基的变化

【Abstract】 The synthsis and biological activity of a Series of new compounds dimedone thiophosphate were described.The structure of these compounds was charactreized by1H NMR,IR and Elementary analysis.The spectrum properties,biological activity and its changes resulting from the difference of substituted groups of these compounds were discussed

【关键词】 待米酮硫代磷酸酯合成生物活性
【Key words】 dimedonethiophosphatesynthesisbiological activity
  • 【分类号】TQ45
  • 【下载频次】65
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