【摘要】 以烟草花叶病毒 (TMV) /烟草为测试体系 ,研究了天然物 PZ1抗病毒 TMV作用机理。在离体及活体条件下 ,PZ1均可抑制病毒核酸与植物核糖体结合。在活体条件下 ,PZ1抑制 TMV- RNA及 TMV蛋白质合成。实验结果表明 PZ1的主要作用靶标为 TMV- RNA更多还原

【Abstract】 The antiviral mechanism of natural product PZ 1 was studied by TMV/tobacco system . The antiviral (TMV) active compound PZ 1 was isolated from Chinese medicine plant. PZ 1 inhibited the combination of viral RNA with plant ribosome both in vitro and in vivo . It also inhibited the synthesis of TMV RNA and TMV protein in vivo . The results assumed that the main target of PZ 1 was TMV RNA.更多还原