【摘要】 目的 :探讨一氧化氮 (NO)在急性白血病诊断、治疗中的作用。方法 :应用硝酸还原酶法检测血清中NO-2 /NO-3 的含量。结果 :急性白血病组血清NO-2 /NO-3 含量与正常对照组比较P <0 0 1;急性非淋巴细胞白血病与急性淋巴细胞白血病血清NO-2 /NO-3 含量比较 ,P >0 0 5。AL患者血清NO-2 /NO-3 含量高组较含量低组完全缓解率高 ,P <0 0 1。结论 :检测血清中NO的水平有助于判断患者的病情及预后更多还原

【Abstract】 Objective:In order to evaluate function of nitric oxide(NO) in diagnosis and treatment of acute leukemia (AL).Methods:The level of serum NO- 2/NO- 3 was measured by nitric acid reducing enzyme method.Results:Comparison of serum NO- 2/NO- 3 between AL group and normal control group,P<001;comparison of serum NO- 2/NO- 3 between acute nonlymphocytic leukemia and acute lymphocytic leukemia,P>005.The high level of serum NO- 2/NO- 3 in acute leukemia patients had higher CR rate compared with low level of serum NO- 2/NO- 3.Conclusion:NO involves the changes of AL,the level of serum NO is helpful to evaluate the state of leukemia patients.更多还原