【摘要】 目的 :探讨质子磁共振波谱(1HMRS)对放射性脑坏死诊断价值。材料和方法 :对2例有脑部肿瘤放疗史临床及CT和MRI难以判断为肿瘤复发或放射性脑坏死和8例病史明确的放射性脑坏死 ,行 1HMRS病灶实质与健侧对应部位对照研究。结果 :2例经手术证实为放射性脑坏死 ,8例放射性脑坏死因病史明确未行手术。放射性脑坏死表现为 :9例NAA、Cr、Cho下降或消失 ,出现Lipid峰 ,NAA/Cr下降 ;1例NAA、Cho、Cr峰均消失 ,仅表现一较平坦的曲线。结论 :1HMRS对放射性脑坏死诊断有重要价值。更多还原

【Abstract】 Objective:To evaluate 1H magnetic resonance spectroscopy(1H MRS) in diagnosing delayed cerebral necrosis.Materials and Methods:Two patients who had clinical and CT,MRI changes that suggested a diagnosis of delayed cerebral necrosis or recurrent brain tumor after radiation therapy and 8 patients who had a clear clinical diagnosis of delayed cerebral necrosis underwent single voxel MR spectroscopy simultaneously both in the lesion’s region and the contralateral side.Results:Two cases who proved by surgicopathology were delayed cerebral necrosis,8 cases who had a clear clinical diagnosis of delayed cerebral necrosis didn’t undergo surgery.Among 10 cases with delayed cerebral necrosis,9 cases exhibited decreased or absent Cho、NAA、Cr and abnormal Lipid,one case showed absent NAA、Cr、Cho with a flat curve.Conclusion:1H MRS is positively claimed for diagnosing delayed cerebral necrosis.更多还原