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顺铂胸腔灌注联合热疗治疗癌性胸水的临床观察
Clinical study of cisplatin injected into thoracic cavity combined with hyperthermotherapy in the treatment of pleural effusion from malignant neoplams
【摘要】 目的:观察热疗结合顺铂(DDP)治疗癌性胸水的疗效。方法:55例癌性胸水患者随机分成两组,治疗组25例DDP胸腔内注入加热疗;对照组单用DDP胸腔内注入。结果:胸水控制有效率治疗组为88.0%,对照组为60.0%,毒副作用相似。结论:热疗+DDP胸腔化疗有协同作用,能有效提高胸水控制率,改善患者生存质量,值得推广使用。
【Abstract】 Purpose: To evaluate the efficacy of cisplatin (DDP) plus hyperthermotherapy in the treatment of pleural effusion from malignant neoplams.Methods: Fifty - five cancer patients with pleural effusion were divided into two groups. Group A (25 cas-es) were treated with DDP injected into thoracic cavity plus hyperthermotherapy. Group B (30 casas) were treated with DDP into thoracic cavity alone. Results: The efficacy of control pleural effusion of Group A:88.0% , and Group B: 60.0% (P<0.05) respec-tively. These were no difference between two groups in toxity. Conclusions: The combination use of hyperthermotherapy and DDP shows evidence of synergitic and additional effect. It can improve the patients’ life quality. It is worth while further studying.
【Key words】 Cisplatin Hyperthermotherapy Pleural effusion from maligrant neoplams;
- 【文献出处】 临床肿瘤学杂志 ,Chinese Clinical Oncology , 编辑部邮箱 ,2000年02期
- 【分类号】R730.5
- 【被引频次】18
- 【下载频次】58