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顺铂胸腔灌注联合热疗治疗癌性胸水的临床观察

Clinical study of cisplatin injected into thoracic cavity combined with hyperthermotherapy in the treatment of pleural effusion from malignant neoplams

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【作者】 周茜菁方青芳裘友好马胜林

【Author】 Zhou Xijing, Fang Qingfang, Qiu Youhao, et al. Zhejiang Province Tumor Hospital, Hang Zhou 310022

【机构】 浙江省肿瘤医院浙江省肿瘤医院 杭州310022杭州

【摘要】 目的:观察热疗结合顺铂(DDP)治疗癌性胸水的疗效。方法:55例癌性胸水患者随机分成两组,治疗组25例DDP胸腔内注入加热疗;对照组单用DDP胸腔内注入。结果:胸水控制有效率治疗组为88.0%,对照组为60.0%,毒副作用相似。结论:热疗+DDP胸腔化疗有协同作用,能有效提高胸水控制率,改善患者生存质量,值得推广使用。

【Abstract】 Purpose: To evaluate the efficacy of cisplatin (DDP) plus hyperthermotherapy in the treatment of pleural effusion from malignant neoplams.Methods: Fifty - five cancer patients with pleural effusion were divided into two groups. Group A (25 cas-es) were treated with DDP injected into thoracic cavity plus hyperthermotherapy. Group B (30 casas) were treated with DDP into thoracic cavity alone. Results: The efficacy of control pleural effusion of Group A:88.0% , and Group B: 60.0% (P<0.05) respec-tively. These were no difference between two groups in toxity. Conclusions: The combination use of hyperthermotherapy and DDP shows evidence of synergitic and additional effect. It can improve the patients’ life quality. It is worth while further studying.

  • 【文献出处】 临床肿瘤学杂志 ,Chinese Clinical Oncology , 编辑部邮箱 ,2000年02期
  • 【分类号】R730.5
  • 【被引频次】18
  • 【下载频次】58
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