【摘要】 目的　 探讨细菌 L型医院感染率、病原学特点及临床特征。方法　 对住院病人采用前瞻性监测 ;进行细菌 L型培养 ,并采用 K- B法进行药敏试验。结果　 71 2 4例住院病人中 ,细菌 L型感染 1 2 6例 ( 1 .77% ) ,烧伤科感染率最高 ,占 9.0 0 % ,其次是肾科 ( 7.1 9% )、血液科 ( 5.1 3% )及小儿科 ( 3.53% )。下呼吸道感染最常见 ( 39.6% ) ,呼吸道症状不典型 ,但受累肺野≥ 2个者占 86.5%。尿路感染者菌落计数 >1× 1 0 5CFU/ ml者占 3.8%。共分离出 1 48株细菌 L型 ,常见的菌种是金葡菌( 2 5.7% ) ,其次为大肠埃希菌和铜绿假单胞菌 (各占 1 6.7% ) ;各种细菌 L型对青霉素、头孢菌素类耐药率高。1 2 6例中治愈 1 0 9例 ,死亡 6例。结论　 细菌 L型医院感染临床上常见 ,表现不典型 ,耐药性严重。更多还原

【Abstract】 Objective To explore the rate of hospital infection caused by bacteria L form,their etiological characteristics and clinical features.Methods The inpatients received prospective monitoring and drug sensitivity test through K B technique.Results Of the 7 124 inpatients investigated,126 cases (1.77%) were infected by bacteria L form.The incidence of infection occurring in the departments of burns,kidney,blood and pediatrics were 9.00%,7.19%,5.13% and 3.53% respectively.The most common infections occurred in the lower respiratory tracts.accounting for 39.6% of the total infections.Mild respiratory symptoms occurred and 86.5% of this kind of patients had more than two lung fields involved.Only a few (3.8%) of the patients with urinary infection had their colony counts more than 1×10 5 CFU/ml.148 strains of bacteria L form were isolated and most of them were S.Aureus (25.7%),E.Coli(16.7%) and Ps.Aeruginose (16.7%)respectively.All these bacteria L forms were found to be markedly resistant to penicillin and cephalosporins.Of the 126 patients,109 were cured and six died of infection.Conclusion Hospital infections caused by bacteria L forms occur frequently in hospital and bacteria L forms are atypical and have high drug resistance.更多还原