【摘要】 目的 :观察单纯激光心肌血运重建 (TML R)术后心肌受损情况。方法 :测定采用高能二氧化碳激光行TML R治疗的 35例冠心病患者术日晨及打孔结束即刻、术后 8h、16 h、2 0 h、2 4h、术后第 2～ 7天 ,血清心肌酶的变化。结果 :术前血清中均未测出肌酸激酶同工酶 (CK- MB)活性 ,术后即刻均开始明显升高 ,术后 2 0 h达到峰值 ,全组平均为 (17.6± 6 .3) IU/ L,术后第 4天 CK- MB活性消失 ,其峰值与打孔数量呈正相关。结论 :TML R术对心肌产生轻微损伤 ,并随着打孔数量的增加而增加 ,但损伤心肌数量较少更多还原

【Abstract】 To observe the postoperative myocardial enzyme’s changing regularity of the transmyocardial laser revascularization (TMLR) as sole therapy to coronary artery disease and to discuss its cause and clinical sense. Method:Within 35 patients with coronary heart disease the venous serum myocardial enzymes were measured on the preoperative morning,postoperatively at once,the 8th,the 16th,the 20th,the 24th hour and every 6 am from the 2nd to the 7th day.Result:The activity of CK MB had not been found in the preoperative serums,but it began to increase obviously just postoperation and to peak level 20 hours later.The average level was ( 17.6 ± 6.3 ) IU/L.The activity of CK MB disappeared on the postoperative 4th day.And the peak level of the enzyme was positively relevant to the numbers of the holes by laser.Couclusion:Mild injury of myocardium may be produced by TMLR.The amount of myocarolial injury is increased with the number of holes,but it is of small amonut.更多还原