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异丙酚麻醉中血浆降钙素基因相关肽及神经降压素改变的观察

The Changes of Plasma CGRP and NT Level in Patients Undergoing General Anesthesia with Propofol

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【作者】 刘刚孙艳林申岱

【Author】 Liu Gang,Sun Yanlin,Shen Dai Department of Anesthesia,Tianjin Medical University General Hospital 300052

【机构】 天津医科大学总医院麻醉科!300052天津医科大学附属口腔医院

【摘要】 目的 :了解异丙酚全身麻醉病人对CGRP及NT的影响。方法 :在 19例病人中采用放免分析的方法测定CGRP及NT水平。结果 :术中和术毕病人血浆CGRP及NT水平较术前均有显著升高。结论 :异丙酚麻醉可增加血浆CGRP及NT水平。推测异丙酚扩张血管、降低血压的作用可能与CGRP及NT的增加有关

【Abstract】 Objective: To examine the changes of CGRP and NT in patients undergoing general anesthesia with propofol.Methods:In 19 patients under propofol anesthesia,the levels of CGRP and NT were detected by means of radio-immunologic analysis.Results:Plasma CGRP and NT levels were dominantly elevated intraoperatively and postoperatively.Conclusion:Propofol anesthesia could increase plasma CGRP and NT.It is proposed that the vasodilating and hypotensive effect of propofol be probably mediated via the increase of plasma CGRP and NT.

  • 【文献出处】 临床麻醉学杂志 ,THE JOURNAL OF CLINICAL ANESTHESILOLGY , 编辑部邮箱 ,2000年02期
  • 【分类号】R971.2
  • 【被引频次】26
  • 【下载频次】57
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