【摘要】 目的 :本研究主要探讨产后雌二醇 (E2 )、孕酮 (P)、催乳素 (PRL )变化和产后抑郁症状间的关系。　方法 :对 38名产妇在产程开始前和产后第 72小时分别抽取血标本 ,使用放射免疫法检测产后 E2 、 P和 PRL 的数量变化 ,同时用 Edingburgh产后抑郁量表 (EPDS)、 Beck抑郁量表(BDI)、一般健康问卷 (GHQ)对产妇在产后第 3天和产后第 42天进行评定。　结果 :产后第 3天 EPDS和 BDI量表分值显著高于产后第 42天 ,产后 E2 变化与 EPDS、 BDI量表分呈显著负相关 ,产后 P变化和产后第 42天 GHQ量表分呈显著正相关 ,PRL 变化和产后情绪状况无明显关系。　结论 :产后内分泌激素变化可能是产后抑郁的病因之一。更多还原

【Abstract】 Objective:To analyze the changes of estradiol (E 2),progesterone (P) and prolactin (PRL),and their relationships with postpartum depression. Method:The blood samples of 38 women were collected before the beginning of labor course and at 72nd hour after childbirth,and the changes of E 2,P and PRL were assayed.Meanwhile these women were assessed with Edingburgh postnatal depression scale (EPDS),Beck depression inventory (BDI) and general health questionnaire (GHQ) at 3rd day and 42nd day. Results:The scores of EPDS and BDI were significantly higher at 3rd day than at 42nd day.The change of E 2 was positively related to the scores of EPDS and BDI,while the change of P was negatively related to the score of GHQ at 42nd day.PRL had no correlation with postpartum emotional status. Conclusion:Changes of hormones may play a role in postpartum depression.更多还原