【摘要】 为观察脑梗死患者脑脊液和血清中脂蛋白 (a)含量的变化 ,选择 80例脑梗死患者和 40例对照者 ,用酶联免疫法测定脂蛋白 (a)在脑脊液及血清中的含量。结果发现 ,脑梗死患者与对照者脑脊液中脂蛋白 (a)含量分别为 2 34± 2 9μg/L及 2 11± 2 1μg/L ,血清中脂蛋白 (a)含量分别为 0 .2 99± 0 .0 2 8g/L及 0 .2 71± 0 .0 2 5g/L ,脑梗死组脑脊液及血清中脂蛋白 (a)含量明显高于对照组 (P <0 .0 1)。脑梗死患者和对照者脑脊液与血清中脂蛋白 (a)水平间均无相关关系 (P >0 .0 5 )。结果提示 ,脑梗死患者脑脊液及血清中脂蛋白 (a)水平明显高于对照者。更多还原

【Abstract】 Aim To educidate the changes of lipoprotein(a) [Lp(a) ] in cerebrospinal fluid (CSF) and serum in patients with cerebral infarction. Methods The CSF and the serum Lp(a) levels were measured with an enzyme-linked immunosorbent assay (ELISA) in 80 patients with acute cerebral infarction and 40 control subjects. [WT5”HZ]Results [WT5”BZ]Lp(a) levels in the CSF and serum of cerebral infarction patients were significanthy higher than that of the controls (234±29 μg/L vs 211±21 μg/L and 0.299±0.028 g/L vs 0.275±0.025 g/L). Lp(a) concentration in the CSF of cerabral infarction patients and controls is not related to that of serum ( P>0.05 ). Conclusion The CSF and the serum Lp(a) levels in patients with cerebral infarction were significantly higher than those in cortrols.更多还原