【摘要】 介绍了国内生产α-异丙基-对氯苯乙酰氯的几种生产工艺路线。提出了以α-异丙基-对氯苯乙酸和氯气为主要原料,在少量硫磺和催化剂存在下合成α-异丙基-对氯苯乙酰氯的新工艺。探讨了温度、时间、催化剂等对反应的影响,分析了产物质量及新工艺的优缺点,并以产物为原料进行了“氰戊菊酯”农药的小试生产。更多还原

【Abstract】 Several processes for the manufacture of α- isopropyl- p -chlorophenylacetyl chloride in our country are introduced. A new process that α- isopropyl- p -chlorophenylacetyl chloride is preparated with α- isopropyl- p -chlorophenylacetic acid and chlorine as the raw materials in the presence of a small amount of sulfur and catalyst is presented. The effects of temperature, time, and catalyst on the preparation are discussed. The quality of the product is analyzed. The advantages and disadvantages of the new process are given, α- Cyano-phenoxybenzyl-2-(4-chlorophenyl)-3-methyl-butyrate is synthesized from said product, NaCN, and m- phenoxybenzaldehyde in the presence of solvent.更多还原