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环氧乙烷对小鼠脊髓神经细胞膜上嵌入蛋白质分布的影响

EFFECTS OF ETHYLENE OXIDE ON DISTRIBUTION OF INSERTING PROTEINS ON NERVE CELL MEMBRANE OF SPINAL CORD IN MICE

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【作者】 陈光忠; 夏国兴; 陆静芬; 钟坤; 张龄;

【Author】 Chen Guangzhong, Xia Guoxin, Lu Jingfen, Zhong Kun, Zhang Ling (Shanghai Medical College for Health Professional, Shanghai 200237)

【机构】 上海职工医学院解剖学教研室!上海200237;

【摘要】 目的:研究环氧乙烷对小鼠神经细胞膜上嵌入蛋白质分布的影响。方法:小鼠每天吸入环氧乙烷2h,持续2或3个月,用冰冻蚀刻电镜观察小鼠腰髓前角神经细胞膜上嵌入蛋白质的分布。结果:随着染毒时间延长,腰髓前角神经细胞膜上的嵌入蛋白质由分布紊乱至成簇聚集。结论:环氧乙烷能改变神经细胞膜上嵌入蛋白质的分布。

【Abstract】 To study effects of ethylene oxide on the distribution of inserting proteins in nerve cell membrane of mice. Methods: The mice were inhaled ethylene oxide for 2 hours every day. After 2 or 3 months, scanning electron microscope with freeze etching was used to observe the distribution of inserting proteins in nerve cell membrane of anterior horn in spinal cord of mice. Results: as the extending of inhaling time inserting proteins distribution changed from turbulence to cluster. Conclusion: Ethylene oxide can change the distribution of inserting proteins in nerve cell membrane.

【基金】 国家自然科学基金资助!(编号39070477)
  • 【文献出处】 解剖学杂志 ,Chinese Journal of Anatomy , 编辑部邮箱 ,2000年01期
  • 【分类号】R994
  • 【被引频次】2
  • 【下载频次】27
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