【摘要】 目的　探讨松果体分泌物直接释放入脑脊液途径的形态学依据 ,　方法　采用常规及 Na OH消蚀法电镜样品制备技术 ,对成年日本猴松果体及其被囊进行了扫描和透射电镜观察。　结果　松果体囊由一层扁平上皮细胞和上皮下结缔组织构成。在面对蛛网膜下隙的囊上皮细胞和细胞间存在许多上皮孔 ;上皮下结缔组织伸入松果体形成小叶间隔 ,将松果体分隔为许多实质小叶。松果体结缔组织的主要成分为胶原纤维 ;实质小叶由大量松果体细胞和少数胶质细胞组成。实质细胞间存在与血管周隙相通的细胞间小管。　结论　细胞间小管 -血管周隙 -囊上皮孔 ,构成了松果体分泌物释放入脑脊液主渠道的结构基础。由此组织信息通道 ,松果体分泌物更易直接被释放入脑脊液而非血液。更多还原

【Abstract】 Objective\ In order to explore the morphological evidence for the pathway for secretions of pineal body releasing directly into the cerebrospinal fluid (CSF). Methods Using the conventional and NaOH macerational methods for preparing electron microscopic specimens, the pineal bodies and its capsules of adult Japanese monkeys were observed with scanning and transmission electron microscope(SEM/TEM). Results The pineal capsule was composed of a layer flattened epithelial cells and a subepithelial connective tissue. The epithelial openings were observed on and among epithelial cells facing the subarachnoid space. The subepithelial connective tissue penetrated the pineal body forming interlobular septum, and separated the pineal body to parenchymal lobules. The chief elements of connective tissue were collagen fibers;The parenchymal lobules were organized with a many pinealocytes and a few glial cells. Between parenchymal cells existed an intercellular canaliculus linking perivascular space. Conclusion Pineal intercellular canaliculus perivascular space epithelial openings made up the structural foundation of the chief channel for secretions of pineal body releasing into CSF. By the tissue channel, pineal secretions is rather easily released directly into CSF than into blood fluid.更多还原