【摘要】 为探讨不育症精子的运动规律及其超微结构的改变,运用计算机辅助的精液分析(CASA),结合扫描电镜检查。结果发现,不育症精子的运动参数:活率、活动力、平均径速度(VAP)明显下降,而运动方式参数直线分离度(STR)却无明显差异,进一步用扫描电镜观察其头颈部,特别是顶体的超微结构,发现不育症精子顶体较大。顶体膜、质膜不完整,不光滑,环状沟不清晰,多呈锯齿状,但胞浆小滴二者大多<1/2且无明显差异(P>0.05)。本文就这些结构差异对生育力的影响作了进一步的探讨,为某些不育症的诊断及疗效的评价提供有效的手段。更多还原

【Abstract】 To study sperm motive regulation and ultrastructure in male infertility CASA (Computer Assisted Sperm Analysis)and SEM(Scan Electronic Microscope)were used. The results were as follows: sperm vigor parameters were all decreased in 12 patients,whereas,pattern parameters had no singnificant difference. By SEM.the results were as follows:infertility group acrosomes were much more bigger than the normal ones. Their acrosome membranes,plasmalemma were not integrativc and not smooth,ringed rips were not clear and zigzag,the plasmatic droplet was 1/2 less than that of the head in both two groups, with no singificant difference, meanwhile, how these abnormal structures affected insemination were analyzed, A conclusion was drawn that CASA and SEM provide effective means to the diagnosis and make an objective appraisal of the treatment of infestility.更多还原