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输血后庚型肝炎的前瞻性研究

A Prospective Study on Post-transfusion Hepatits G

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【作者】 陈志军刘彩云王和平孙德贵贾文龙刘洪海刘景龙于爱林王佑春张华远

【Author】 Chen Zhijun, et al (Sanitation & Antiepidemic Station of Guan County,065500)

【机构】 河北省固安县卫生防疫站!065500河北省固安县人民医院中国药品生物制品检定所中国药品生

【摘要】 为探讨输血后庚型肝炎的发病率,1997 年2 月开始,我们采用前瞻性研究方法,对102名住院输血病人进行了12 个月的随访研究。113 名献血员提供的113 份血液中单纯ALT 异常率3-5 % (4/113) ,抗- HGV阳性率8-9 % (10/113) ,抗- HCV 阳性率3-5 % (4/113) ;输血后HGV 感染率为3-8 % (4/102) ;10 人输入抗- HGV 阳性血,输血后HGV 感染4 例,其中PT- HG2 例,PT- HG潜伏期38 ~62 天,平均45 天;抗- HGV 最早检出时间为输血后38 天,最迟为96 天,平均为63-5 天;PT- HC发病率为4-9% (5/102) ,5 例PT- HC 中4 例输入抗- HCV 阳性血,1 例输入单纯ALT异常血,PT- HCV 感染率为100 % ,证实HGV 可经血传播,HG 的慢性化程度较高,HGV可形成慢性携带;抗- HCV 阳性血具有很强的传染性。

【Abstract】 To investigate the morbidity rate of post-transfusion Hepatitis G,we followed up 102 transfused patients in hospital for 12 months with a prospective study method from Feb,1997.In all of 113 blood samples provided by 113 blood donors, abnormal simple ALT rate was 3.5%(4/113). Anti-HGV positive rate was 8.9%(10/113). Anti-HCV positive rate was 3.5%(4/113).Ten of 102 patients were transfused by anti-HGV positive blood, 4 of them were infected with HGV and 2 patients were PT-HG.The infection rate of HGV after transfusion was 3.8%(4/102).The incubation time of PT-HG was 38-62 days, average 45 days. Anti-HGV could be detected since 38 days to 96 days after transfussion, average 63.5 days. The incidence rate of PT-HC was 4.9%(5/102). Of 5 patients 4 were transfused by anti-HC positive blood and 1 was transfused by simple ALT abnormal blood. It was proved that HGV could be transmitted by transfusion and formed a chronic virus carrier.

  • 【文献出处】 疾病监测 ,DISEASE SURVEILLANCE , 编辑部邮箱 ,2000年01期
  • 【分类号】R512.6
  • 【被引频次】2
  • 【下载频次】16
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