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喹赛多体外抑菌试验

Antibacterial Activity in vitro of Cyadox

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【作者】 范盛先袁宗辉王大菊孔科陈品马敬忠

【Author】 Fan Shengxian Yuan Zonghui Wang Daju Kong Ke Chen Pin Ma Jingzhong (Huazhong Agricultural University,Wuhan 430070,China)

【机构】 华中农业大学兽药研究所!武汉430070

【摘要】 用管碟法测定喹赛多对 9种共 1 5株畜禽常见病原菌的体外抑菌活性。喹赛多对革兰氏阴性菌和革兰氏阳性菌都有较强的抑菌活性 ,对鸡大肠杆菌的最低抑菌浓度 (MIC)为 0 .6 2 5 μg/ml、鸡巴氏杆菌为 1 .2 5 μg/ml、金色葡萄球菌为 2 .5 μg/ml,可见对革兰氏阴性菌的抑菌作用略强于革兰氏阳性菌。其抑菌活性比金霉素弱 ,与喹乙醇相近 ,比磺胺二甲嘧啶强。结果表明 ,喹赛多是一种较强的抑菌剂 ,可作为添加药物用于预防畜禽常见病原菌感染

【Abstract】 The antibacterial activity of cyadox against 9 species 15 strains of pathogen was determined by means of cylinder plate methed .The minimal inhibitory concentration(MIC) of cyadox against Escherichia coli, Pasterella multocide and Staphylococcus aureus was 0.625μg/ml,1.25μg/ml and 2.5μg/ml, respectively. The result indicated that cyadox had slightly stronger antibacterial activities against grampositive bacterial than gramnegtive bacterial. The antibacterial activity of cyadox was weaker than that of aureomycin,close to olaqindox and stronger than sulfadimidiner. Cyadox maybe alternatives to olaquindox, as additive, for preventing animal from bacterial infection and promoting growth.

【关键词】 喹赛多管碟法抑菌活性
【Key words】 cyadoxcylinder plate methedantibacterial activity
【基金】 “九五”国家和农业部重点科技攻关资助项目! (编号 :96 0 0 9 0 2 0 4)
  • 【文献出处】 华中农业大学学报 ,JOURNAL OF HUAZHONG AGRICULTURAL , 编辑部邮箱 ,2000年01期
  • 【分类号】S859.79
  • 【被引频次】54
  • 【下载频次】311
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