【摘要】 在金属镝的促进下,醛、酮可与炔丙基溴反应,高选择性高产率地得到相应的高炔丙醇,没有发现连二烯醇的存在.当用苯基炔丙基溴代替炔丙基溴与醛、酮反应时,主要得到了相应的连二烯醇,而没有发现高快丙醇的存在,由此提出了六元环过渡态的反应机理.更多还原

【Abstract】 Promoted by metal dysprosium, aldehydes and ketones could react smoothly with propargyl bromide to afford the corresponding homopropargylic alcohols in good to excellent yields, and no allenic alcohols were found. However, carbonyl compounds only afford the corresponding allenic alcohols when propargyl bromide was replaced by 1 - phenyl - 3 - bromopropargyl bromide, and no homopargylic alcohols were formed.更多还原