【摘要】 在碱性条件下 ,用氯乙酸对壳聚糖进行化学改性研究 ,合成了有良好水溶性的羧甲基壳聚糖。通过胶体滴定测定羧甲基取代程度。优化反应条件为 :反应温度65°C,反应时间 8h,氢氧化钠浓度 30 % ,投料比 :壳聚糖∶氯乙酸 =1∶ 6(质量比 )。更多还原

【Abstract】 Chitosan was modified with chloroacetic acid in the presence of sodium hydroxide. Carboxymethyl chitosan with good water solubility was synthesized, the amount of carboxymethyl in the product was determinated by colloid titration. The optimum reaction condition was ratio of chitosan∶chloroacetic acid=1∶6 (massratio), temperature 65°C, the time 8 h, concentration of sodium hydroxide 30%.更多还原