节点文献

8-Br-cAMP对肺癌NSCLC-3细胞凋亡相关基因表达的影响

Effects of 8-Br-cAMP on expression of related apoptotic gene in human lung cancer NSCLC-3 cell line

推荐 CAJ下载
PDF下载
不支持迅雷等下载工具，请取消加速工具后下载。

【Author】 CHEN Kuisheng 1) ,OUYANG Songyun 2) ,JIANG Guozhong 1) ,GAO Dongling 1) ,ZHANG Yunhan 1) ,MA Lijun 2) ,SUN Peizong 2) 1)Department of Pathology,Henan Medical University,Zhengzhou 450052 2)Department of Respiratory Medicine ,

【机构】河南医科大学病理教研室!郑州450052；河南医科大学一附院呼吸内科!郑州450052；

【摘要】目的 :观察 8 Br cAMP对人肺癌NSCLC 3细胞凋亡相关基因表达的影响。方法 :将体外培育的NSCLC 3细胞分为实验组和对照组 ,采用原位杂交方法观察 8 Br cAMP对NSCLC 3细胞c myc、bcl 2基因表达的影响。结果 :8 Br cAMP处理后的实验组较未加 8 Br cAMP的对照组c myc、bcl 2基因表达降低 (P <0 0 1)。结论 :8 Br cAMP可下调与NSCLC 3细胞凋亡相关的c myc、bcl 2基因表达。更多还原

【Abstract】 Aim: To observe the effects of 8 Br cAMP on expression of the related apoptotic gene in human lung cancer NSCLC 3 cells.Methods: The cultured NSCLC 3 cells in vitro were divided into the experimental and the control groups.The effects of 8 Br cAMP on expression of c myc and bcl 2 in NSCLC 3 cells were observed by in situ hybridization.Results:The expression of c myc and bcl 2 in the experimental group was weaker than that in the control group( P <0.01).Conclusion: 8 Br cAMP could suppress the related apoptotic gene expression of c myc and bcl 2 in NSCLC 3 cells.更多还原

【关键词】 8-Br-cAMP；细胞凋亡；原位杂交；
【Key words】 Br cAMP； cell apoptosis； in situ hybridization；

【基金】河南省教委自然科学基金资助课题!19993 2 0 0 11

【文献出处】河南医科大学学报 ,JOURNA OF HENAN MEDICAL UNIVERSITY , 编辑部邮箱 ,2000年03期

【分类号】Q786
【被引频次】2
【下载频次】34

知网节下载

节点文献中：

本文链接的文献网络图示:

本文的引文网络

节点文献