【摘要】 应用KLH和SEA皮试法 (intraderminaltest,IDT)在血吸虫病疫区对加藤法粪检确诊的 32例阳性人群和31例阴性人群作平行检测。结果显示 :KLH 和SEA IDT二法与粪检阳性符合率分别为 90 %和 1 0 0 % ,差异无显著性(P >0 .0 5) ;KLH 和SEA IDT与粪检阴性符合率为 71 9%和 2 5 % ,差异有高度显著性 (P <0 .0 1 ) ;在 31例粪检阴性人群中 ,两IDT检出均为阳性者 9例 ,SEA IDT单一阳性者 1 5例 ,KLH IDT无 1例为单一阳性。在双皮试检出阳性者中经粪孵毛蚴法追踪 ,查出 2例阳性 ,而SEA IDT单阳者中无 1例阳性 ;2 7例治后 1年的人群中 ,KLH IDT检出 6例阳性 ,阴转率为 77 8% ,SEA IDT检出 2 1例阳性 ,阴转率为 2 2 2 %。提示 :KLH作为诊断抗原用于现场皮试不仅具有较高的敏感性而且有较好的考核疗效价值更多还原

【Abstract】 Thirty three egg positive subjects and 32 egg negative subjects were tested synchronously by KLH IDT and SEA IDT in endemic area of schistosomiasis. Compared with stool examination, the positive coincidence rate of KLH IDT and SEA IDT were 90% and 100%, respectively, which showed no statistical significance(P>0.05), and the negative coincidence rate of KLH IDT and SEA IDT were 71.9% and 25%, respectively, which showed statistical significance(P<0.01). Of the 31 egg negative subjects, 9 subjects showed positive by both SEA IDT and KLH IDT, and 15 subjects showed positive by SEA IDT but negative by KLH IDT. Both double positive subjects and single positive subjects were examined further by miracidium hatching test, there were 2 subjects showing positive among the 9 double positive subjects. In addition, of 27 subjects that had been treated one year before, only 6 subjects showed positive by KLH IDT, the reversion rate was 77.8%; whereas, the reversion rate was 22.2%(6/21) by SEA IDT. The results suggest that KLH IDT has high value in diagnosing schistosomiasis, particularly shows a potential in assessing therapeutic efficacy of schistosomiasis. [更多还原