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20例胃肠道粘膜相关淋巴瘤的临床病理分析
Clinical and Pathological Anlysis of 20 Cases of Gastrointestinal Mucosa-associated Lymphoid Tissue Lymphoma
【摘要】 目的 探讨胃肠道MALT淋巴瘤的病理特征及其与临床的联系。方法 收集 2 0例胃肠道MALT淋巴瘤 ,采用病理组织学和免疫组化标记技术对其进行临床及病理资料分析。结果 2 0例胃肠道MALT淋巴瘤中 ,男性发病率高于女性 ,男女比率 2 3∶1。平均年龄 48 2岁 ( 2 2~ 65岁 )。临床表现无特异性。发病部位以贲门最多见 ,其次为回盲部。病理学以低度恶性淋巴瘤多见 ,经免疫组化标记证实全部为B细胞性淋巴瘤。结论 本病误诊率较高 ,应尽量使用免疫组化技术对其进行鉴别诊断 ,必要时可借助电镜及基因表型分析。抗幽门螺旋杆菌的治疗应引起足够认识。
【Abstract】 Objective To study the clinical and pathological features of patients with gastrointestinal mucosa associated lymphoid tissue(MALT) lymphoma.Methods 20 patients with gastrointestinal MALT lymphoma were analyzed Results It was found that the mobidity of gastrointestinal MALT lymphoma in the male was more than that in the female with a ratio of 2.3∶1.The average age was 48.2 with a range from 22 to 65.The clinical manifestations were not specific,but mainly digestive symptoms and abdominal masses.Most cases occurred in cardia and ileocaecalis,and pathologically lowgrade lymphomas were predominant.All cases were confirmed by immunohistochemistry and were entirely of B cell lymphoma.Conclusions The results suggested that much attention should be paid to the differential diagnosis of gastrointestinal MALT lymphoma.So did anti Helicobacter pylori therapy.
- 【文献出处】 河南肿瘤学杂志 ,HENAN JOURNAL OF ONCOLOGY , 编辑部邮箱 ,2000年02期
- 【分类号】R735.3
- 【下载频次】45