【摘要】 观察化疗药物及高聚金葡素对癌性心包积液的治疗效果。方法 :将临床收治的癌性心包积液患者随机分为A、B两组 ,A组 2 8例 ,心包腔内注入mmc6～ 8mg ,5 -Fu5 0 0～ 75 0mg ,Dexamethason5～ 1 0mg ,高聚金葡素 2 0 0 0～ 5 0 0 0u。B组 2 2例 ,心包腔内注药同A组 ,但不加高聚金葡素。A、B两组在治疗前先抽取心包内积液 1 0 0～ 75 0ml,用药后 2h内让患者辗转身体 ,使药物在心包腔内分布均匀 ,每例用药 1～ 5次。结果 :按WHO浆膜腔积液疗效标准将疗效分为CR、PR、NC ,A组有效率 46 43% ,B组为 31 82 % ,统计学比较无显著性差异 (P>0 0 5 )。结论 :化疗及高聚金葡素对癌性心包积液有效 ,化疗加高聚金葡素的有效率高于单纯化疗组 ,但两者差异无统计学意义。更多还原

【Abstract】 To observe the curative effect of chemotherapy drugs and staphylococcin aureus to matastatic carerous pericardial effusion.Methods:The matastatic carcerous pericardial effusion patients were divided into A and B group in clinics randomly.28 cases A group patients were injected with MMC,5-Fu,Dexamethasone and staphylococcin aureus intra-pericardial cavity.22 cases B group were treated nearly same but without staphylococcin aureus as control group.Both groups evacuate the effusive fluid 100～750ml before treatment,then injected the different drugs and moved patients’ body so that to make the drugs uniform distribution 1～5 times per case.Results:According to the WHO standard of serous cavity effusion treatment the curative effect were divided into CR,PR and NC.The curative rate in A group was 46.43% and B group 31.82%.Conclusion:The treatment of chemotherapy and staphylococcin aureus were effective to the matastatic carcerous pericardial effusion.Its effect were higher than control group but there was no statistical significance.更多还原