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葛根黄豆甙元衍生物抗醉酒作用的实验研究
The Action of Against Alcohol by Daidzein and its Series Derivations
【摘要】 为筛选葛根黄豆甙元系列衍生物是否具有抗醉酒作用的药效,本实验采用40%乙醇所致动物中枢抑制的方法进行研究,结果显示 Daidzein Ⅰ号药样品(简称 DZⅠ)具有明显的抗醉酒作用。同时,DZⅠ大鼠的血中乙醇浓度的降低更有力地证明了这一结论。
【Abstract】 In order to select the action of against alcohol of daidzein and its series derivations,we adopt the method of antral nervous system depression used 40% alcohol.The result of these experiments show that the sixth derivation of Daidzein(DZ1)has significant effect of against alcohol.The result is also proved powerfully by the decrease of ethanol concentration in rat blood after oral admistration DZ1 and ethand.
【关键词】 葛根黄豆甙元衍生物;
中枢抑制;
血中乙醇浓度;
【Key words】 Daidzein and its series derivations; Antral nervous system; Ethanol concentration in rat blood;
【Key words】 Daidzein and its series derivations; Antral nervous system; Ethanol concentration in rat blood;
- 【文献出处】 黑龙江医药 ,Heilongjiang Medical Journal , 编辑部邮箱 ,2000年05期
- 【分类号】R285
- 【被引频次】32
- 【下载频次】95