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Carnoy’s液和三氯乙酸对牙源性角化囊肿作用的实验研究

A Study of the Effects of Carnoy’s Solution and Trichloracetic Acid on Odontogenic Keratocysts

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【作者】 卫晋雄赵怡芳李宏礼陈新明熊世春

【Author】 Wei Jinxiong,Zhao Yifang,Li Hongli,et al Department of Oral and Maxillofacial Surgery,Stomatological College,Hubei Medical University,Wuhan 430070,China

【机构】 武汉口腔医学院颌面外科!武汉430070

【摘要】 选择 2 8例确诊的牙源性角化囊肿 ,用Carnoy’s液和三氯乙酸处理 2 0min后 ,切取囊壁组织进行组织学、组织化学、酶组织化学、透射电镜等检查。结果显示角化囊肿囊壁上皮酶活性丧失 ,胶原纤维断裂 ,细胞核变性。说明Carnoy’s液和三氯乙酸破坏了囊壁活性 ,有助于减少角化囊肿术后复发。

【Abstract】 Objective:To investigate the histomorphological change of keratocysts after spreading cyst walls with Carnoy’s solution and 20% Trichloracetic Acid(TCA).Methods:28 consecutive cases of keratocysts diagnosed clinically by means of radiology and pathology were employed.Distinct areas of cyst walls in vivo were spread with two agents for 20 minutes simultaneously.Results:The decline of elasticity and ready removal of cyst walls were noticed.Disruption and disintegration of overlying epithelium and loss of activity of acid phosphatase were observed histologically.Injuries of similar degrees of cystic tissues under two agents were remarked and less infiltrative potential of 20% TCA was revealed.Conclusion:This study suggests that treatment of cyst walls with Carnoy’s solution and TCA during an enucleation procedure may destroy cystic tissues and result in the reduction of recurrence rate after operation.

【关键词】 牙源性囊肿/治疗三氯乙酸
【Key words】 odontogenic cyst/THtrichloracetic acid
  • 【文献出处】 湖北医科大学学报 ,JOURNAL OF HUBEI MEDICAL UNIVERSITY , 编辑部邮箱 ,2000年03期
  • 【分类号】R782.2
  • 【被引频次】11
  • 【下载频次】77
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