【摘要】 采用丙烯基硫脲 30 0mg/ (kg·d)连续 3d经腹腔注射感染日本血吸虫 42d的小鼠 ,停药后 2h进行解剖 ,结果发现 :丙烯基硫脲对日本血吸虫雌雄成虫生长发育及雌虫卵巢长度无明显影响 (P >0 .0 5 ) ,而雌虫子宫内则出现无卵或虫卵形状不规则 ,呈沙粒状小团块物 ,未见明显虫卵卵壳。提示丙烯基硫脲作为酚抑制剂能有效抑制日本血吸虫雌虫成虫产卵更多还原

【Abstract】 Thiosinamines was injected peritoneally at the dosage of 300 mg/(kg·d) 3 days on end into the mice who had been infected with Schistosoma Japonicum for 42 days,then dissected them 2 hours after stopping giving them medicine.The results indicated that there was no apparent effect on the growth of the male and female adults and the length of the ovaries of the females (P>0.05);however,no eggs or irregular eggs appear in their uterus;also some sandy mass could be seen,but no obvious shells.These suggest that thiosinamine can suppress the oviposition of female adults of Schistosoma Japonicum.更多还原