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紫云金的抗炎镇痛作用
Anti-inflammatory and Analgesic Effect of Zi Yun Jin
【摘要】 紫云金系紫草、白芷、冰片、银花等的醇提物 ,ig紫云金 2~ 4g· kg- 1对大鼠角叉菜胶性足跖肿胀 ,大鼠棉球肉芽肿增生及小鼠巴豆油性耳廓水肿均有显著的抑制作用。可抑制醋酸所致的腹腔毛细血管通透性的增加。紫云金对小鼠醋酸扭体反应具有显著的抑制作用。能显著的提高小鼠热刺激的痛阈水平。提示 ,紫云金具有抗炎 ,镇痛作用
【Abstract】 Zi Yun Jin was isolated from red root gromwel root dahurian angelica root bomeo camphor and honeysuckble.Zi Yun Jin 2~4g·kg -1 ig inhibited hind paws swelling induced by sc 0.15ml carrageenan and inhibited maekedly proliferation of granuloma induced by sc implantation of cotton-pellets in rats.Zi Yun Jin 2~4g·kg -1 ig inhibited markedly the ear swelling induced by croton oil and the increased vascular permeability induced by ip 0.7% HAC in mice.It also decreased the writhins and had anaglesin with hot-plat in mice.The Yesult Showed Zi Yun Jin had significantly anti-inflammatory and analgesic effects.
【Key words】 Red root gromwel root; Dahurian angelica root; Anti-inflammatory; analgesic;
- 【文献出处】 海峡药学 ,STRAIT PHARMACEUTICAL JOURNAL , 编辑部邮箱 ,2000年01期
- 【分类号】R285
- 【被引频次】32
- 【下载频次】99