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高原肺水肿患者血清肌红蛋白和血乳酸浓度的变化
CHANGES OF LEVEL OF SERUM MYOGLOBIN AND LACTIC ACID IN PATIENTS WITH HAPE
【摘要】 探讨高原肺水肿 (HAPE)患者血清肌红蛋白 (Mb)和血乳酸 (BLA)的变化 ;方法 :于海拔 3 70 0m处医疗站对收治的 8例HAPE患者治疗前和临床治愈后进行Mb及BLA检测 ;结果 :HAPE患者治疗前较临床治愈后Mb和BLA均升高 ,有极显著性差异 (P <0 .0 1) ;结论 :HAPE时机体存在心肌损伤 ,乳酸性和非乳酸性两类氧债的存在 ,是HAPE急性缺氧应激性机制中的一个重要环节。
【Abstract】 To study changes of level of serum myoglobin and blood lactic acidin patients with HAPE at 3 700m altitude.Methods:8 cases with HAPE,exposed to 4 800m high altitude for 3~5 days,were performed for serum myoglobin and blood lactic acid before and after treatment with drugs at 3 700m.Results:The level of myogiobin and lactic acid were significantly increased before cure compared with after treatment (P<0.01).Conclusions:Injury of myocardium,oxygen debt resulted from factors of non-lactic acid and lactic acid induced-hypoxia,is a important cause in incidencdof HAPE.
【Key words】 High altitude; HAPE; Lactic acid; Myogokbin; Serum/biochemistry;
- 【文献出处】 高原医学杂志 ,JOURNAL OF HIGH ALTITUDE MEDICINE , 编辑部邮箱 ,2000年01期
- 【分类号】R446.1
- 【被引频次】2
- 【下载频次】37