【摘要】 测定了１５名长时间从事低剂量铅接触的女工血铅、铜、锌、铁、锰及铜锌超氧化物歧化酶（Ｃｕ－Ｚｎ　ＳＯＤ）活性、脂质过氧化产物二级降解物丙二醛（ＭＤＡ）含量，并以同年龄组同地区非铅暴露人群作对照。结果显示：暴露组的血铅、铜、ＭＤＡ含量高于对照组（Ｐ＜０．０５）；而血锌、 Ｃｕ－Ｚｎ ＳＯＤ活性低于对照组（Ｐ＜ ０．０５）；血 Ｍｎ、 Ｆｅ两组无明显差异（ Ｐ＞ ０．０５）。提示：长期接触低浓度铅可诱发体内脂质过氧化，同时引起微量元素含量改变。更多还原

【Abstract】 Lead and other trace elements copper, zinc, manganese, iron as well as Cu-Zn-superox- ide dismutase (Cu-Zn SOD) activity and MDA content in the blood of 15 women-workers who were exposed to low-dose lead during long time were determined. The result showed that compared with the control group, the average content of Pb, Cu and MDA in lead exposed group significantly increased(P< 0.05), while Zn content and SOD activity were lower. It sugguests that longterm expose to low-dose lead can cause blood lead increased, the disorder of lipid peroxidation and the relevant changes of trace elements content.更多还原