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长期低浓度铅暴露对人体微量元素的影响
Trace Elements and Lipid Peroxidation Changes in Workers with Longterm Exposed to Low-dose Lead
【摘要】 测定了15名长时间从事低剂量铅接触的女工血铅、铜、锌、铁、锰及铜锌超氧化物歧化酶(Cu-Zn SOD)活性、脂质过氧化产物二级降解物丙二醛(MDA)含量,并以同年龄组同地区非铅暴露人群作对照。结果显示:暴露组的血铅、铜、MDA含量高于对照组(P<0.05);而血锌、 Cu-Zn SOD活性低于对照组(P< 0.05);血 Mn、 Fe两组无明显差异( P> 0.05)。提示:长期接触低浓度铅可诱发体内脂质过氧化,同时引起微量元素含量改变。
【Abstract】 Lead and other trace elements copper, zinc, manganese, iron as well as Cu-Zn-superox- ide dismutase (Cu-Zn SOD) activity and MDA content in the blood of 15 women-workers who were exposed to low-dose lead during long time were determined. The result showed that compared with the control group, the average content of Pb, Cu and MDA in lead exposed group significantly increased(P< 0.05), while Zn content and SOD activity were lower. It sugguests that longterm expose to low-dose lead can cause blood lead increased, the disorder of lipid peroxidation and the relevant changes of trace elements content.
- 【文献出处】 广东微量元素科学 ,TRACE ELEMENTS SCIENCE , 编辑部邮箱 ,2000年01期
- 【分类号】R135
- 【被引频次】8
- 【下载频次】107