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大鼠睾丸摘除后胰岛变化的实验研究

EXPERIMENTAL STUDIES OF THE PANCREATIC ISLET CHANGE AFTER TESTECTOMY

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【作者】 蔡秋云张艳熊希凯

【Author】 Cai Qiuyun, Zhang Yan, Xiong Xikai (Department of Anatomy, Tongji Medical University, Wuhan 430030 China)

【机构】 同济医科大学解剖学教研室!武汉430030

【摘要】 雄性健康大白鼠 1 4只 ,2只为正常对照 ,1 2只摘除双侧睾丸 ,在电镜下观察 :大鼠胰岛数目显著减少。胰岛β细胞的β颗粒数目也减少 ,β颗粒的致密核心皱缩、变小呈乾枯状态。线粒体畸形变 ,呈分叉状 ;内质网数目减少。β细胞与毛细血管之间亮区没有β颗粒。动物体重显著增加

【Abstract】 adult male rats were divided into 2 groups: 2 were in normal control group, 12 had bilateral testec tomy. The results showed that there were ultrastructural changes: the number of pancreatic islet was markedly decreased in 14 days after testectomy, so were the β granulles of pancreatie β cells. The dense granulles became small and dry in β granulles. Mitochondria were in abnormality and divergent form. The number of endoplasmic reticulum was decreased. β granules were absent in the space between blood capillaries and β cells. The rat obviously gained weight 14 days after testectomy.

【关键词】 睾丸摘除胰岛超微结构大鼠
【Key words】 TestectomyPancreatic isletUltrastructuralRat
  • 【文献出处】 中国组织化学与细胞化学杂志 ,CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY , 编辑部邮箱 ,2000年01期
  • 【分类号】Q95-3
  • 【下载频次】40
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