【Abstract】 Two novelβ cyclodextrin derivatives containing 1,2 benzisoselenazol 3(2H) one have been synthesized by a convenient method in 60% and 55% yields, respectively, and characterized by elemental analysis, IR and 1H NMR. The superoxide dismutase (SOD) activity of these modified β cyclodextrins has been determined by the method of autooxidation of pyrogallol at 298.15 K in buffer solution(pH = 8.20). The results obtained indicate that these cyclodextrin derivatives possesses relatively high SOD activity up to 179~330 U/mg.更多还原