【摘要】 目的　探讨老年肺癌患者行全肺切除的可行性和预后。方法　自 1 985～ 1 995年 ,我们对2 3例 6 5岁以上非小细胞肺癌 (NSCLC)患者行全肺切除 ,选择同期小于 6 5岁行全肺切除的 99例NSCLC患者作为对照 ,比较两组病例 5年生存率、手术并发症和死亡率、手术前后肺功能的改变。生存率分析采用Kaplan Meier法。结果　老年组 5年生存率与对照组相似 (2 7.5 6 %比 30 .5 1 % ,P >0 .0 5 ) ,但手术并发症和死亡率明显高于对照组 (1 3.0 4%比 2 .0 2 % ,P <0 .0 5 )。结论　全肺切除术对老年NSCLC患者仍然合适 ,但因手术合并症和死亡率较高 ,故应认真选择手术适应证更多还原

【Abstract】 Objective To study the probability and prognosi s after pneumonectomy for NSCLC in the elderly. Methods From 1985 to 1995, pneumonectomy was performed in 122 patients with non small cell lung cancer. Of the 122 patients, 23 cases were 65 years old or older (study group) a nd the other 99 cases were less than 65 years old. Five year survival, operativ e co mplications and mortality, and change of lung functions before and after operati on were compared between the two groups. Kaplan meier m ethod was used to analyzed the survival. WTHZ Results The 5 year sur vival for the study group was similar to that for the control group (27.56％ WTBX vs WTBZ 30.51％, WTBX P WTBZ ＞0.05), but the mortality in the study group was sign ificantly higher than that in the control group (13.04％ WTBX vs WTBZ 2.02 ％, WTBX P WT BZ ＜0.05). There was no significant difference between the pre operative and po st operative lung function for both groups. WTHZ Conclusion Pneumone ct omy in elderly patients with NSCLC appears to be applicable. However, it shoud b e performed only in carefully selected patients because of the increased operati ve risk and death.更多还原