【摘要】 【目的】　探讨胎儿宫内生长迟缓（ＩＵＧＲ） 与免疫因素的相关性。【方法】　ＥＬＩＳＡ 法检测２５ 例足月小样儿脐血、母血肿瘤坏死因子α（ＴＮＦα） 水平。【结果】　足月小样儿组脐血和母血ＴＮＦα水平均明显高于正常新生儿组，但足月小样儿出生体重与脐血、母血ＴＮＦα水平间皆无相关性。【结论】　胎儿ＩＵＧＲ 与ＴＮＦα水平增高有一定关联，足月小样儿宫内发育过程中可能受到异常免疫状态的影响。更多还原

【Abstract】 Objective To explore the correlation between fetal intrauterine growth retardation(IUGR) and immune factes. Methods The levels of TNF α in cord blood from 25 cases of small for gestational age(SGA) infants and peripheral vein blood from 25 cases of mothers were detected by way of double antibody sandwich ELISA. Results The levels of TNF α in cord blood and mother’s peripheral blood from SGA infant group was significantly higher than that from normal full term infant group.There were no significant correlationship between birth weight of SGA 1 infants and TNF α levels in cord blood or mother’s peripheral blood. Conclusion There was some correlation between fetal IUGR and elevated TNF α levels.The results suggested that intrauterine growth of SGA infants had probaly been influenced by abnormal immune state.更多还原