【摘要】 采用茶多酚 (TP)处理老年小鼠 ,并用3 H-甲基掺入法测定了成年和老年小鼠肝DNA甲基化酶的活性。以传统抗衰老中药人参作阳性对照 ,结果证明TP和 0 2 %的人参汤剂能明显提高老年小鼠肝细胞DNA甲基化酶的活性 ,具有延缓衰老的作用 ,为从分子生物学角度探讨TP延缓衰老的机理提供了依据更多还原

【Abstract】 The Polyphenols(TP) and Ginseng decoction have been given to the senile mice and the DNA methylating enzyme activity in the liver of mature mice and senile mice has been detected with the 3H - methyl incorporation method.Result showed that the TP and 0 2% Ginseng decoction obviously enhanced the DNA methylating enzyme activity in the liver cell in senile mice,thus showed the effect of anti senility.This investigation provided the evidence for studying the mechanism of TP in anti senility from the viewpoint of molecular biology.更多还原