【摘要】 目的　观察生长抑素制剂 (施他宁、善得定 )对于肝硬化食道胃底静脉曲张破裂出血的治疗效果 ,并与垂体后叶素进行比较。方法　 6 4例患者随机分为垂体后叶素组 (n =2 1)、施他宁组 (n =2 0 )、善得定组 (n =2 3)进行治疗。结果　垂体后叶素组、施他宁组和善得定组患者自接诊后至完全止血时的出血量 ,及接诊后至止血后 4 8小时生命体征基本平稳时的输血量无显著性差异 (P >0 0 5)。各治疗组 2 4小时内的止血率均为 80 %左右 (P >0 0 5)。结论　我们认为生长抑素作为肝硬化食道胃底静脉破裂出血治疗方法的一种选择 ,疗效肯定 ,但近期治疗效果并不明显优于垂体后叶素。更多还原

【Abstract】 Objective To evaluate efficacy of somatostatin on treatment of hepatic cirrhosis with acute esophageal gastric variceal bleeding. Methods 64 hepatic cirrhosis patients with acute esophageal variceal bleeding were divided into 3 groups:vasopressin group ( n =21),stilamin group ( n =20),sandostatin group ( n =23). Results The results showed that the amount of bleeding and blood transfusion from admitting to 48 hours after hemostasis were similar in vasopressin,somatostatin and sandostatin group ( P >0 05) and the initial hemostasis ratio within 24 hours in every group was similar (approximately 80%).更多还原