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眼球表面鳞状细胞性肿物的临床病理学分析

The clinicopathological analysis of ocular surface squamous neoplasia.

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【作者】 林锦镛; 李恩江; 陈瑰;

【Author】 Lin Jin yong,Li En jiang,Chen Gui Tianjin Eye Hospital,Tianjin,300040

【机构】 天津眼科医院!300040;

【摘要】 目的:提高对眼球表面鳞状细胞性肿物的诊断和治疗水平。方法:对天津眼科医院1978~1997年收治的180例眼球表面鳞状细胞性肿物进行临床和病理学分析。结果:本组病变可分为三大类:1良性病变73例(40.4%),包括鳞状细胞增生、乳头状瘤和假上皮瘤样增生;2交界性病变42例(23.3%),主要是非典型增生;3恶性病变65例(35.9%),包括原位癌、鳞状细胞癌和粘液表皮样癌。本组病变好发于角膜缘部位(118例),男性多见(145例),通常为单眼发病,多数发病时间为半年~1年内。手术后复发主要与肿物切除不彻底有关。结论:对眼球表面鳞状细胞性肿物的术前正确诊断、手术设计和手术边缘的病理学检查是非常重要。

【Abstract】 To improve the level of diagnosis and treatment for ocular surface squamous neoplasia (OSSN).Methods:The 180 cases of OSSN treated in Tianjin Eye Hospital from 1978 1997 were analysed by clinical and pathological methods.Results:These lesions may divide into three types:(1)benign lesions 73 cases(40.4%),including squamous cell hyperplasia,papilloma,and pseudo epitheliomatous hyperplasia;(2)intermediate lesions 42 cases (23.3%),mainly dysplasia;(3)malignancy lesions 65 cases (35.9%),including carcinoma in situ,squamous cell carcinoma and muco epidermoid carcinoma.118 cases occured in limbus and 145 cases were males.The duration of symtomas of major cases ranged from 6~12 months.Recurrences were related to inadequate surgical margins.Conclusion:The accuracy diagnosis of preoperation,surgical design and pathological examination of surgical margins are very important.

  • 【文献出处】 中国实用眼科杂志 ,Chinese Journal of Practical Opht , 编辑部邮箱 ,1999年10期
  • 【分类号】R739.7
  • 【被引频次】2
  • 【下载频次】53
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