【摘要】 目的 :观察夏连抑幽胶囊治疗幽门螺杆菌 (HP)感染性胃炎的疗效 ,系统地开发研究“经方”。方法 :将HP感染性胃炎患者随机分为两组 ,治疗组 136例 ,用夏连抑幽胶囊治疗 ,对照组 90例 ,用丽珠得乐胶囊治疗 ,均治疗 4周 ,观察临床疗效 ,并作相应的动物实验。结果 :临床结果显示夏连抑幽胶囊在改善临床症状 ,消除粘膜炎症 ,清除HP方面均较对照组为优 (P <0 0 5 ,P <0 0 1)。动物实验结果表明 ,夏连抑幽胶囊对抗炎、镇痛、胃溃疡模型的影响均有显著作用 ,与对照组比较有显著性差异 (P <0 0 5 ,P <0 0 1)。结论 :夏连抑幽胶囊治疗幽门螺杆菌感染性胃炎疗效肯定。更多还原

【Abstract】 Objective: To observe the therapeutic effect of Xialian Yiyou Capsule (XLYYC) on helicobacter pylori (HP) infected gastritis to develop the serial Chinese classical recipe. Methods: HP infected patients were divided into two groups, 136 patients in the XLYYC group treated with XLYYC and 90 patients in the control group treated with Lizhu Dele Capsule, for 4 weeks as one therapeutic course, the clinical therapeutic effect was observed, and corresponding animal experiments were done. Results: Clinical effect of the XLYYC group was better than that of the control group in improving clinical symptoms, relieving inflammation of gastric mucosa and eliminating HP (P<0 05, P<0 01). Results of animal experiment showed that XLYYC was superior than the control significantly in anti inflammation, analgesia, stomach emptying and curing gastric ulcer model (P<0 05, P<0 01). Without any adverse reaction has been found in acute toxicologic study. Conclusion: The therapeutic effect of XLYYC in treating HP infected gastritis was definite and safe, non toxic.更多还原