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薏苡仁油抗肿瘤作用研究
The Study on Antineoplastic Effect of Coix Seed Oil
【摘要】 薏苡仁油5-4g/kg 对小鼠移植性S180 肉瘤抑制率两次试验均达到30 % 以上,1-8g/kg 、5-4g/kg 对小鼠移植性HAC 肝癌抑制率两次试验亦均达到30 % 以上。薏苡仁油1-8g/kg 可显著增加小鼠腹腔巨噬细胞吞噬鸡红细胞的吞噬率,5-4g/kg 组对小鼠NK 细胞活性也有明显增强作用
【Abstract】 Objective: To evaluate the antineoplastic effect of Coix seed oil as health food, and study its mechanism preliminarily. Method: According to 《Procedures and methods of function evaluation for health food》, select the mice bearing transplanted cancer of S 180 sarcoma and HAC liver cancer as animal models. Results: The inhibitory rate of Coix seed oid 5.4g/kg to S 180 was both above 30% for twice, and of 1.8g/kg、5.4g/kg to HAC liver cancer was also above 30%. The Coix seed oil 1.8g/kg and 5.4g/kg could increase the phagocytic activities of peritoneal macrophanges to chicken RBC and the activities of NK cells of mice respectively. Conclusion: The Coix seed oil has a distinct antineoplastic effect on S 180 and HAC.
【Key words】 Coix seed oil; mice transplanted cancer; phagocytosis; NK cells;
- 【文献出处】 中药药理与临床 ,PHARMACOLOGY AND CLINICS OF CHINESE MATERIA MEDICA , 编辑部邮箱 ,1999年06期
- 【分类号】R285
- 【被引频次】71
- 【下载频次】562