【摘要】 目的研究在心血管效应中枢调节机制中神经递质间的关系。方法收集家兔脑脊液，用放免法和荧光分光技术测定侧脑室注射乙酸胆碱（ACh）后，P物质（SP）和去甲肾上腺素（NA）、肾上腺素（A）含量的改变。结果侧脑室注射．ACh后，SP含量较生理盐水对照组明显升高，而NA和A的含量则明显降低。结论脑内ACh可刺激SP能神经元释放SP，而抑制去甲肾上腺素能和肾上腺素能神经元释放NA和A。更多还原

【Abstract】 Objective The relation to central transmittels substance in the cardiovascular effects wassludied. Methods Radioimmunoassay (RIA) and fluorometry were used to determie the changes ofsubetance P-like inimunoreactivity (SPLI) and catecholamine in cerebrospinal fluid afterintracerebroventricular acetycholine (ACh). Results The incroue of SPLI and the decrease ofnoradrenalin (NA) and adrenalin (A) contents in cerebrospinal fluid after intracerebroventricularacetylcholine . Conclusions Releasing SP is excited or Relouing NA and A are inhibited, by ACh inbrain.更多还原