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精浆免疫抑制物(SPIM)活性低下与反复自然流产关系及中药治疗的研究

Interrelative studies between recurrent spontaneous abortion and activated decrease of SPIM along with it’s traditional Chinese medical therapy.

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【作者】 王永征李霞

【Author】 Wang Yongzheng,Li Xia.(Clinic of Sterility and Infertility,Weifang Medical College,Weifang,Shandong,261042)

【机构】 山东潍坊医学院不孕不育门诊

【摘要】 1对正常生育组84对及反复自然流产组的186对夫妇进行了研究。用抗补体法对丈夫精浆测定SPIM活性,结果表明:反复自然流产组SPIM活性3892±615×103u/L低于正常生育组4386±664×103u/L,差异显著(P<0.01)。说明SPIM活性低下是反复自然流产的原因之一。2用“升抑汤”对75例SPIM活性低下的患者作1-3个疗程的治疗,SPIM活性由3482±521×103u/L上升到4263±618×103u/L,治疗前后差异显著(P<0.01)。治疗后与正常生育组相比差异无显著性,这说明“升抑汤”是治疗SPIM活性低下的有效方剂。

【Abstract】 Using anticomplement method to measure the activity of seminal plasma immnological materials (SPIM) of husbands seminal plasma (SP),We have studied these two groups 84 normal couples versus 186 couples affected by recurrent spontaneous abortion (RSA).The results indicated that the average SPIM activated values of RSA groups was 389.2±61.5×10 3U/L and was lower than that of normal groups which was 438.6±66.4×10 3U/L.By comparison,here was significant difference between them.That showed that activated decrease of SPIM was the main cause of RSA. 2.One to three therapy courses were also preaented to 75 individuals affected with SPIM activated decrease,using "Shengyitang".We found that their averageactivity of SPIM was increased from 348.2±52.1×10 3U/L to 426.3±61.8×10 3U/L.The significant difference existed by comparing protherapy to posttherapy while there was no significant difference between posttherapy group and no mal group.The outcome showed that "Shengyitang" offered the best hope for treating activated decrease of SPIM.

  • 【文献出处】 中国优生与遗传杂志 ,CHINESE JOURNAL OF BIRTH HEALTH & HEREDITY , 编辑部邮箱 ,1999年03期
  • 【分类号】R714.21
  • 【被引频次】3
  • 【下载频次】62
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