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核糖核酸对慢性肝病患者血清HA、LN、Ⅳ-C、PCⅢ的影响

Effects of RNA on HA、 LN、Ⅳ-C、PC Ⅲ in Serum of the Patients with Chronic Hepatits

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【作者】 黄加权; 李小舟; 丁红芳; 张东绅; 黄元成; 宋建新; 齐俊英; 田德英;

【Author】 Huang Jiaquan, Li Xiaodan, Din Hongfang, et al. Department of Infections Diseases Tongji Hospital, Tongji Medical University, (Wuhan, 430030)

【机构】 同济医科大学附属同济医院; 恩施州人民医院; 同济医科大学附属同济医院 430030; 445000; 430030; 430030;

【摘要】 目的:观察RNA抗肝纤维化疗效。方法:应用RNA治疗慢性肝炎130例,肝硬变48例,并设甘利欣对照组。结果:治疗组血清白蛋白及肝纤维化指标中的HA、LN、Ⅳ-C、PCⅢ明显下降,复常率明显高于对照组(P<0.05)。结论:RNA能降低慢性肝痛中血清HA、LN、Ⅳ-C、PⅢ的水平,其抗纤维化作用可能是通过保护和修复肝细胞膜而达到的。

【Abstract】 Aim: To study the effect of RNA on liver fibrosis. Methods: 178 Cases of chronic heptitis and hepatocir-rhosis were treated with a two-month course of intermuscular injection of RNA or diammonium glycyrrhizinate respectively. Result: The results showed serum albumin and the four indexes of hepatofibrosis (hyaluronic acid, laminin collagen type Ⅳ ,PⅢ P) of the observation group were better than those of the control group. Conclusion : It is suggested that RNA has the effects of protecting liver cells and anti-hepatic fibrosis.

  • 【文献出处】 中西医结合肝病杂志 ,Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases , 编辑部邮箱 ,1999年06期
  • 【分类号】R575
  • 【被引频次】1
  • 【下载频次】34
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