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儿童颅脑损伤后癫痫的高危因素研究

Factors influencing posttraumatic epilepsy in children with head trauma.

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【作者】 史志东何穗智蔡梅钦陈爱慈林木田胡裕全杨李轩

【Author】 Shi Zhidong, He Huizhi, Cai Meiqin, Chen Aichi, Lin Mutian, Wu Yuquan and Yang Lixuan. Department of Neurosurgery, Third Affiliated Hospital, Sun Yatsen University of Medical Sciences, Shipai Gangding, Guangzhou. 510630. Tel:020 85516867 2230

【机构】 中山医科大学第三附属医院!510630中山医科大学基础学院数学教研室中山医科大学第三附属医院!510630中山医科大学第三附属医院!510630

【摘要】 目的 分析儿童颅脑损伤后并发癫痫的危险因素。方法 对286 例年龄6 个月至14 岁的颅脑损伤住院患者,采用 Logistic 模型分析 G C S 评分、意识状态及 C T 结果等10 种因素与颅脑损伤后癫痫的关系。结果 单因素分析显示: G C S评分、意识状态及 C T 结果与颅脑损伤后癫痫有关,经多因素分析,仅 G C S 评分有意义。结论 儿童颅脑损伤后癫痫与 G C S评分≤8 分、意识障碍及 C T 结果异常有关,上述因素同时存在时,仅 G C S 评分≤8 分是颅脑损伤后癫痫的危险因素。

【Abstract】 Objective To study the clinical predictors of posttraumatic epilepsy(PTE) in children with head trauma. Methods Our clinical sample included 286 children aged 6 months to 14 years admitted to Department of Neurosurgery with a diagnosis of head trauma. A Logistic model with 10 variables such as consciousness, GCS, CT results and so on was used to analyse the factors contribution to PTE in the children.Results Among the 10 variables, the three variables of consciousness, GCS and CT results are related to PTE with the single data in Logistic model, but only GCS is related to it with the multivariate data in Logistic model. Conclusions For the pediatric head trauma patients, GCS≤8, loss of consciousness and an abnormal CT scan were all associated with PTE. However, only a low GCS(GCS≤8) was predictive of PTE when these factors were considered simultaneously.

  • 【文献出处】 中国神经精神疾病杂志 ,CHINESE JOURNAL OF NERVOUS AND MENTAL DISEASES , 编辑部邮箱 ,1999年05期
  • 【分类号】R651.15
  • 【被引频次】4
  • 【下载频次】57
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