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血清维生素A、SIL-2R水平与食管癌关系的研究
The study on the relationship between levels of Vitamine A soluble interleukin 2 receptor in serum and esophageal cancer
【摘要】 目的:探讨血清维生素A、SIL2R 水平与食管癌的关系。方法:以微量荧光法和ELISA 法分别对32 例术前食管癌病人和32 例健康对照者同步进行了血清维生素A 和SIL2R 水平的测定。结果:食管癌患者血清中具有抗亚硝胺致癌作用的维生素A 水平较对照组低( P< 001) 的同时,血清SIL2R 水平显著高于对照组( P< 001) ,IL2 依赖性免疫功能降低。结论:食管癌患者显示的血清维生素A 水平降低和SIL2R 水平升高可能与患者的免疫功能异常有关,并提示在食管癌的发生中,血清维生素A的降低和SIL2R 的升高可能存在着某种联系。
【Abstract】 Objective:To study the relationship between levels of Vitamine A (Vit A)soluble interleukin 2 receptor in serum and esophageal cancer.Methods:Using methods of microfluorescence and ELISA,the levels of Vit A and SIL 2R in serum were determined for 32 esophageal cancer patients and 32 health controls.Results:The level of Vit A in serum function of the esophageal cancer group was lower than the control group ( P <0 01),which can resist nitrosamine cause cancer,but the level of SIL 2R in serum of the esophageal cancer group was higher than the control group ( P <0 01)at the same time.Conclusion:The immunologic functions depend on IL 2 of the patients might be inhibited.There was probably relationship between the low Vit A level and the high SIL 2R level in serum and the abnormal immunologic functions of the patients with esophageal cancer.The result point out it was possible that there was a relationship between Vit A level and SIL 2R contents.
【Key words】 Vitamine A Soluble interleukin 2 receptor Esophageal cancer;
- 【文献出处】 中国免疫学杂志 ,CHINESE JOURNAL OF IMMUNOLOGY , 编辑部邮箱 ,1999年09期
- 【分类号】R735.1r#
- 【被引频次】2
- 【下载频次】49