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肝细胞生长因子修复关节软骨缺损超微结构的观察

ULTRASTRUCTRURAL OBSERVATION OF HGF IN THE RESTORATION OFGAPPED CARTILAGE

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【作者】 周珍; 孙树勋; 张洪斌; 曹世义;

【Author】 Zhou Zhen;Sun Shuxu;Zhang Hongbin,etc. (Department of Microscope, North China Coal Medical College,Tangshan 063000)

【机构】 华北煤炭医学院电镜室!河北省唐山市; 063000; 唐山市第二医院整形外科; 华北煤炭医学院附属医院外科;

【摘要】 目的探讨肝细胞生长因子(HGF)对关节软骨缺损修复的作用。方法将健康大耳白兔 20只,分成4组,选右膝为实验组,左膝为对照组。结果造成软骨缺损后,膝关节腔注射HGF及盐水,于不同时间,对损伤修复组织进行电镜观察。结论实验证明HGF有利于软骨组织修复。

【Abstract】 Objective To study the effect of HGF on the restorationof the gapped cartilage. Method 25 healthy big--eared white rabbits were divided into four groups, with their right knees forming the test group and their. left knees the control group. The rabbits were injected with HGF and NaCl seperately into the knee cavity after cartilage gapswere made. Ultrastructural observation was carried out with TEM. ResultThe test group had formed cartilaginous tissue while the control group and scarred tissue. Conclusion HGF can be useful andfavourable to the restoration ofarticular cartilage.

【关键词】 软骨; 修复; 超微结构;
【Key words】 cartilage restoration ultrastructure;
  • 【文献出处】 中国煤炭工业医学杂志 ,CHINESE JOURNAL OF COAL INDUSTRY MEDICINE , 编辑部邮箱 ,1999年03期
  • 【分类号】R684
  • 【被引频次】1
  • 【下载频次】20
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